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Changes in attentional processes in Parkinson's Disease

(Project leader: Ori Peleg)

 

Non-motor symptoms, such as cognitive dysfunction, have been recognized as a prominent part of Parkinson's Disease (PD), and can precede diagnosis of motor symptoms by several decades. We have begun to investigate how various aspects of attention – including alerting, exogenous and endogenous orienting, and executive control – are affected in the various clinical stage of PD. We hope not only to reveal how disease progression affects attention, but also to support the development of better diagnostic and evaluative tools for PD, as well as achieving better understanding of the brain substrates of PD-caused changes in attention, using hemodynamic imaging.

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The study is conducted in collaboration with Prof. Anat Mirelman and Dr. Inbal Maidan of the Brain & Neurological Disorders Research Institute, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine of Tel-Aviv University.

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